I had the same question myself a few months ago. I finally chose Node.js, and it was one of the best options I did back then. From when I started programming, I always believed that Python was for me the best language, secure and stable. However, it is not flexible for web development, there are more packages & libraries that are built and work only with JavaScript / TypeScript, and the community, resources & support is much bigger. I was also fascinated by the Django ORM, which I still am, & the admin interface. But those are things, that can be replaces by other tools, such as TypeORM, and the admin interface was not needed at all finally for my case. I know understand that Python is not the language that I should use everywhere and every time, but I can say that it is really good for algorithms, computer science, maths, statistics, analytics & AI. To be honest, I chose TypeScript (TS) with Node.js & Express, because it has auto-completion and "strict" code checking. I hope this helps you, and let you take a look at various aspects of choosing a programming language to work with.